Bepc, Inc has an open position for a Research Associate II in South San Francisco, CA!!
W2 Contract 3 years
Pay and Benefits-$38-$44 an hour-Medical, Dental, Vision, Paid Life Insurance
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department.
The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins. Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening. Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion. Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
...innovative lift truck solutions and services, but also consulting, engineering design, installation and service of automated equipment and... ...solutions. Pengate Handling Systems is searching for an Industrial Engineer to join our team! This individual will work closely...
YULA High School is looking for an energetic, passionate and experienced coach to serve as the Women's JV Basketball Coach at YULA High School Girls Division. Our school is seeking an applicant who will teach and mold these young women into student-athletes. You must possess...
HK Solutions Group is seeking a CIPP Construction Laborer . Position can be based in Watertown, SD, Sioux Falls, SD or Rogers, MN. The position... ...CDL will earn $70,000+ annually!Year-round work. No experience required. CDL (Commercial Driver License) is preferred but...
After a family has been investigated, a Family Based Safety Services (FBSS) worker helps them make changes to protect their children from abuse and neglect and keep them safe at home. This involves providing services offered by the agency, the family's community, and their...
...revisions, customer priority shifts, or unplanned disruptions (machine downtime, material delays). What We Are Looking For: Bachelor... ...of experience in production or manufacturing planning in a job shop or high-mix machining environment. Strong proficiency in ERP...